CMap Candidate Details

Structure:
CMap ID: C30333
Pert ID: BRD-K87991767
Compound Name: umbelliferone
Targets: CA9
MoA: Cyclooxygenase inhibitor
SMILES: Oc1ccc2ccc(=O)oc2c1
InchiKey: ORHBXUUXSCNDEV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1790 BRD-K87991767 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2002 BRD-K87991767 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2441 BRD-K87991767 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2523 BRD-K87991767 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39213 BRD-K87991767 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39514 BRD-K87991767 A549 10 uM 6 h -0.22 -0.93 0.07 0.21 0.74 0.03
39808 BRD-K87991767 ASC 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.35 2.01
40364 BRD-K87991767 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40526 BRD-K87991767 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40905 BRD-K87991767 NEU 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.27
41228 BRD-K87991767 NPC 10 uM 24 h -0.23 -0.96 0.1 -0.24 -0.8 0.12
41568 BRD-K87991767 SKB 10 uM 24 h -0.28 -1.15 0.44 -0.34 -1.15 1.06
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).