CMap Candidate Details

Structure:
CMap ID: C30342
Pert ID: BRD-K88025533
Compound Name: fingolimod
Targets: S1PR1; S1PR3; S1PR5; S1PR4
MoA: Immunosuppressant; Sphingosine 1 phosphate receptor agonist
SMILES: CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1
InchiKey: KKGQTZUTZRNORY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95543 BRD-K88025533 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95679 BRD-K88025533 U2OS 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
118374 BRD-K88025533 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118485 BRD-K88025533 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118531 BRD-K88025533 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121746 BRD-K88025533 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121777 BRD-K88025533 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121810 BRD-K88025533 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121826 BRD-K88025533 MCF??7.00 10 uM 24 h -0.23 -0.96 0.1 -0.38 -1.28 1.45
121854 BRD-K88025533 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121877 BRD-K88025533 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129852 BRD-K88025533 HEK293 0.03 uM 24 h 0.14 0.6 0.0 0.0 0.0 0.0
129929 BRD-K88025533 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129977 BRD-K88025533 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130063 BRD-K88025533 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130134 BRD-K88025533 THP1 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).