CMap Candidate Details
Structure:
| CMap ID: | C30388 |
| Pert ID: | BRD-K88186167 |
| Compound Name: | GW-4064 |
| Targets: | NR1H4 |
| MoA: | FXR agonist |
| SMILES: | CC(C)c1onc(c1COc1ccc(C=Cc2cccc(c2)C(O)=O)c(Cl)c1)-c1c(Cl)cccc1Cl |
| InchiKey: | BYTNEISLBIENSA-MDZDMXLPSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 90451 | BRD-K88186167 | HL60 | 10 uM | 2 h | -0.23 | -0.96 | 0.1 | 0.0 | 0.0 | 0.0 |
| 90461 | BRD-K88186167 | HT29 | 2.22 uM | 24 h | 0.32 | 1.35 | 0.96 | -0.3 | -1.01 | 0.56 |
| 98948 | BRD-K88186167 | NEU | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.86 | 0.15 |
| 99257 | BRD-K88186167 | NPC | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |