CMap Candidate Details

Structure:
CMap ID: C30420
Pert ID: BRD-K88304388
Compound Name: dextrorphan
Targets: OPRD1; OPRK1; OPRM1
MoA: Glutamate receptor antagonist
SMILES: CN1CC[C@]23CCCC[C@@H]3[C@@H]1Cc4ccc(O)cc42
InchiKey: JAQUASYNZVUNQP-PVAVHDDUSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24499 BRD-K88304388 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24699 BRD-K88304388 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24963 BRD-K88304388 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25114 BRD-K88304388 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.45 -1.53 15.35
25267 BRD-K88304388 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25541 BRD-K88304388 VCAP 10 uM 6 h 0.31 1.29 0.67 0.38 1.34 1.72
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).