CMap Candidate Details

Structure:
CMap ID: C30442
Pert ID: BRD-K88358234
Compound Name: xaliproden
Targets: HTR1A
MoA: Serotonin receptor agonist
SMILES: FC(F)(F)c1cccc(c1)C1=CCN(CCc2ccc3ccccc3c2)CC1
InchiKey: WJJYZXPHLSLMGE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2137 BRD-K88358234 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2657 BRD-K88358234 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39809 BRD-K88358234 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40099 BRD-K88358234 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40906 BRD-K88358234 NEU 10 uM 24 h -0.28 -1.17 0.5 0.0 0.0 0.0
41229 BRD-K88358234 NPC 10 uM 24 h 0.0 0.0 0.0 -0.49 -1.64 15.65
41569 BRD-K88358234 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127728 BRD-K88358234 A375 1.11 uM 24 h 0.23 0.96 0.08 -0.35 -1.19 1.16
127768 BRD-K88358234 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127845 BRD-K88358234 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127919 BRD-K88358234 HUVEC 1.11 uM 24 h 0.0 0.0 0.0 -0.19 -0.65 0.01
127973 BRD-K88358234 MCF10A 3.33 uM 24 h -0.25 -1.03 0.2 0.31 1.1 0.7
128041 BRD-K88358234 PC3 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.38
128065 BRD-K88358234 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.32
135521 BRD-K88358234 HA1E 0.01 uM 24 h 0.25 1.05 0.17 0.0 0.0 0.0
135546 BRD-K88358234 HELA 0.25 uM 24 h -0.29 -1.21 0.57 0.0 0.0 0.0
135597 BRD-K88358234 HT29 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135637 BRD-K88358234 JURKAT 0.08 uM 24 h -0.2 -0.84 0.01 0.26 0.92 0.25
135686 BRD-K88358234 MCF??7.00 0.01 uM 24 h 0.3 1.26 0.56 -0.28 -0.94 0.37
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).