CMap Candidate Details

Structure:
CMap ID: C30506
Pert ID: BRD-K88573743
Compound Name: A-443654
Targets: --
MoA: --
SMILES: CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OC[C@H](CC4=CNC5=CC=CC=C54)N
InchiKey: YWTBGJGMTBHQTM-IBGZPJMESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
72 BRD-K88573743 BJAB 0.125 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
115 BRD-K88573743 HBL1 10 uM 4 h 0.0 0.0 0.0 0.31 1.08 0.66
157 BRD-K88573743 K562 0.66 uM 4 h -0.23 -0.97 0.11 -0.25 -0.85 0.2
197 BRD-K88573743 KMS34 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
236 BRD-K88573743 NALM6 0.125 uM 24 h 0.39 1.63 1.57 0.22 0.79 0.07
276 BRD-K88573743 OCILY10 0.01 uM 24 h 0.18 0.77 0.0 -0.26 -0.89 0.27
298 BRD-K88573743 OCILY19 0.04 uM 24 h 0.27 1.13 0.29 -0.28 -0.95 0.4
356 BRD-K88573743 OCILY3 2.5 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
393 BRD-K88573743 SKMEL5 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
432 BRD-K88573743 THP1 0.01 uM 4 h 0.27 1.13 0.28 -0.32 -1.08 0.8
451 BRD-K88573743 TMD8 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92411 BRD-K88573743 A375 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92438 BRD-K88573743 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92470 BRD-K88573743 BT20 0.04 uM 24 h 0.29 1.19 0.42 0.24 0.86 0.15
92504 BRD-K88573743 HA1E 0.04 uM 24 h 0.27 1.11 0.25 0.0 0.0 0.0
92538 BRD-K88573743 HME1 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92583 BRD-K88573743 HS578T 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92632 BRD-K88573743 HT29 0.37 uM 24 h 0.0 0.0 0.0 -0.2 -0.68 0.02
92673 BRD-K88573743 LNCAP 0.04 uM 24 h 0.31 1.3 0.69 0.0 0.0 0.0
92738 BRD-K88573743 MCF10A 0.37 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92759 BRD-K88573743 MCF??7.00 1.11 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92774 BRD-K88573743 MDAMB231 0.04 uM 24 h 0.2 0.85 0.0 0.0 0.0 0.0
92809 BRD-K88573743 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92830 BRD-K88573743 SKBR3 0.04 uM 24 h 0.26 1.07 0.19 -0.3 -1.02 0.61
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).