CMap Candidate Details

Structure:
CMap ID: C30558
Pert ID: BRD-K88701661
Compound Name: dimercaptosuccinic-acid
Targets: DNMT1
MoA: Chelating agent
SMILES: OC(=O)[C@@H](S)[C@@H](S)C(O)=O
InchiKey: ACTRVOBWPAIOHC-XIXRPRMCSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
44628 BRD-K88701661 A549 10 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.83
45046 BRD-K88701661 ASC 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.71 0.04
45333 BRD-K88701661 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.36 1.26 1.29
45593 BRD-K88701661 HT29 10 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.52
45724 BRD-K88701661 MCF??7.00 10 uM 24 h 0.27 1.13 0.29 0.28 0.99 0.39
46471 BRD-K88701661 PHH 10 uM 24 h -0.22 -0.9 0.04 0.0 0.0 0.0
96364 BRD-K88701661 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96435 BRD-K88701661 PC3 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.64
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).