CMap Candidate Details

Structure:
CMap ID: C30570
Pert ID: BRD-K88742110
Compound Name: PCI-34051
Targets: HDAC6; HDAC1; HDAC8; HDAC10
MoA: HDAC inhibitor
SMILES: COc1ccc(Cn2ccc3ccc(cc23)C(=O)NO)cc1
InchiKey: AJRGHIGYPXNABY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
47381 BRD-K88742110 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
48909 BRD-K88742110 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
49730 BRD-K88742110 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
90522 BRD-K88742110 PC3 0.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98778 BRD-K88742110 NPC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
99104 BRD-K88742110 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
119191 BRD-K88742110 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119247 BRD-K88742110 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119279 BRD-K88742110 HCC515 10 uM 24 h 0.0 0.0 0.0 0.34 1.22 1.15
119306 BRD-K88742110 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119333 BRD-K88742110 HT29 0.37 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.55
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).