CMap Candidate Details

Structure:
CMap ID: C30576
Pert ID: BRD-K88761633
Compound Name: BRD-K88761633
Targets: GBA
MoA: Glucosylceramidase inhibitor
SMILES: CCOC(=O)c1ccccc1S(=O)(=O)N1CCN(CC1)c1nc(nc2ccccc12)-c1cccs1
InchiKey: UONYMHZUNCSOPQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
16396 BRD-K88761633 A375 10 uM 6 h 0.35 1.45 1.12 0.0 0.0 0.0
16802 BRD-K88761633 A549 10 uM 6 h 0.26 1.08 0.22 0.28 1.0 0.42
17127 BRD-K88761633 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
17467 BRD-K88761633 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
17810 BRD-K88761633 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
18070 BRD-K88761633 MCF??7.00 10 uM 24 h -0.24 -1.02 0.17 0.24 0.84 0.12
18513 BRD-K88761633 PC3 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.22 1.24
18857 BRD-K88761633 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.86 0.22
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).