CMap Candidate Details

Structure:
CMap ID: C30604
Pert ID: BRD-K88849294
Compound Name: lobaric-acid
Targets: PTPN1
MoA: Tyrosine phosphatase inhibitor
SMILES: CCCCCc1c(C(=O)O)c(O)cc2OC(=O)c3c(cc(OC)cc3Oc12)C(=O)CCCC
InchiKey: JHEWMLHQNRHTQX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6810 BRD-K88849294 A375 10 uM 24 h -0.22 -0.92 0.06 -0.34 -1.14 1.02
7198 BRD-K88849294 A549 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.82
7491 BRD-K88849294 HA1E 10 uM 6 h 0.29 1.2 0.42 0.25 0.89 0.21
7922 BRD-K88849294 HT29 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
8116 BRD-K88849294 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8533 BRD-K88849294 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8850 BRD-K88849294 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).