CMap Candidate Details

Structure:
CMap ID: C03065
Pert ID: BRD-K02079473
Compound Name: oxatomide
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: O=c1[nH]c2ccccc2n1CCCN1CCN(CC1)C(c1ccccc1)c1ccccc1
InchiKey: BAINIUMDFURPJM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91143 BRD-K02079473 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
122862 BRD-K02079473 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122901 BRD-K02079473 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.55
122942 BRD-K02079473 HELA 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
122977 BRD-K02079473 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123026 BRD-K02079473 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123116 BRD-K02079473 MDAMB231 10 uM 24 h 0.24 0.99 0.1 0.29 1.02 0.48
123149 BRD-K02079473 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123187 BRD-K02079473 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131213 BRD-K02079473 A375 2.22 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.3
131249 BRD-K02079473 A549 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131363 BRD-K02079473 HUVEC 0.08 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
131403 BRD-K02079473 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.42
131441 BRD-K02079473 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131500 BRD-K02079473 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).