CMap Candidate Details

Structure:
CMap ID: C30667
Pert ID: BRD-K89015388
Compound Name: GSK-923295
Targets: --
MoA: --
SMILES: CC(C)Oc1ccc(cc1Cl)C(=O)N[C@H](CNC(=O)CN(C)C)Cc1ccc(cc1)-c1cn2cccc([C@H](C)O)c2n1
InchiKey: WHMXDBPHBVLYRC-OFVILXPXSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121739 BRD-K89015388 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121820 BRD-K89015388 MCF??7.00 1.11 uM 24 h 0.2 0.82 0.0 -0.27 -0.9 0.28
121847 BRD-K89015388 PC3 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.23 1.25
129761 BRD-K89015388 A375 2.22 uM 24 h 0.22 0.91 0.04 -0.24 -0.82 0.15
129838 BRD-K89015388 HEK293 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129876 BRD-K89015388 HELA 2.22 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.16
129899 BRD-K89015388 HT29 2.22 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.11
129922 BRD-K89015388 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129964 BRD-K89015388 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130049 BRD-K89015388 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130120 BRD-K89015388 THP1 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130166 BRD-K89015388 YAPC 2.22 uM 24 h -0.28 -1.16 0.47 -0.36 -1.21 1.24
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).