CMap Candidate Details

Structure:
CMap ID: C30730
Pert ID: BRD-K89208535
Compound Name: indacaterol
Targets: ADRB2
MoA: Adrenergic receptor agonist
SMILES: CCc1cc2CC(Cc2cc1CC)NC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12
InchiKey: QZZUEBNBZAPZLX-QFIPXVFZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127731 BRD-K89208535 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127773 BRD-K89208535 A549 10 uM 24 h 0.23 0.96 0.08 0.28 0.99 0.41
127813 BRD-K89208535 HA1E 1.11 uM 24 h 0.25 1.04 0.14 0.0 0.0 0.0
127851 BRD-K89208535 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127897 BRD-K89208535 HT29 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.59
127925 BRD-K89208535 HUVEC 10 uM 24 h -0.22 -0.91 0.06 0.0 0.0 0.0
127979 BRD-K89208535 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.6
128022 BRD-K89208535 MCF??7.00 10 uM 24 h -0.23 -0.96 0.1 -0.41 -1.39 2.02
128043 BRD-K89208535 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128070 BRD-K89208535 YAPC 10 uM 24 h 0.0 0.0 0.0 0.39 1.38 2.16
135552 BRD-K89208535 HELA 2.22 uM 24 h 0.31 1.3 0.72 0.0 0.0 0.0
135643 BRD-K89208535 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 -0.25 -0.86 0.2
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).