CMap Candidate Details

Structure:
CMap ID: C30742
Pert ID: BRD-K89237706
Compound Name: noscapine
Targets: SIGMAR1
MoA: Tubulin inhibitor; Bradykinin receptor antagonist
SMILES: COc1ccc2[C@H](OC(=O)c2c1OC)[C@@H]3N(C)CCc4cc5OCOc5c(OC)c34
InchiKey: AKNNEGZIBPJZJG-QNSVNVJESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
13880 BRD-K89237706 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
14177 BRD-K89237706 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
14540 BRD-K89237706 HA1E 10 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.55
14910 BRD-K89237706 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
15154 BRD-K89237706 HT29 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.49
15409 BRD-K89237706 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
15844 BRD-K89237706 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
15940 BRD-K89237706 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).