CMap Candidate Details

Structure:
CMap ID: C30753
Pert ID: BRD-K89274813
Compound Name: DMP-543
Targets: --
MoA: --
SMILES: Fc1cc(CC2(Cc3ccnc(F)c3)c3ccccc3C(=O)c3ccccc23)ccn1
InchiKey: MUJBUUDUXGDXLW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2138 BRD-K89274813 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.05 0.69
2707 BRD-K89274813 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40106 BRD-K89274813 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40914 BRD-K89274813 NEU 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
41237 BRD-K89274813 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41577 BRD-K89274813 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127733 BRD-K89274813 A375 0.125 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.58
127775 BRD-K89274813 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127815 BRD-K89274813 HA1E 10 uM 24 h -0.32 -1.35 0.98 0.0 0.0 0.0
127854 BRD-K89274813 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.35 1.25 1.28
127928 BRD-K89274813 HUVEC 0.37 uM 24 h -0.24 -1.01 0.16 0.0 0.0 0.0
127982 BRD-K89274813 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.5
128044 BRD-K89274813 PC3 0.04 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
135555 BRD-K89274813 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135603 BRD-K89274813 HT29 0.25 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.86
135646 BRD-K89274813 JURKAT 0.25 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
135689 BRD-K89274813 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
135738 BRD-K89274813 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).