CMap Candidate Details

Structure:
CMap ID: C30965
Pert ID: BRD-K89930444
Compound Name: AG-592
Targets: --
MoA: --
SMILES: Oc1ccc(/C=C(C#N)/C(=O)NC2CCC(CC3CCC(CC3)NC(=O)C(=Cc4ccc(O)c(O)c4)C#N)CC2)cc1O
InchiKey: VEPQEAOWDILSHB-KOJZRSEWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1657 BRD-K89930444 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
2140 BRD-K89930444 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2226 BRD-K89930444 PC3 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
2543 BRD-K89930444 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
39219 BRD-K89930444 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39363 BRD-K89930444 A549 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.45 15.35
39817 BRD-K89930444 ASC 10 uM 24 h 0.28 1.18 0.39 -0.4 -1.35 2.02
40109 BRD-K89930444 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40371 BRD-K89930444 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40531 BRD-K89930444 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.51 -1.72 15.65
40917 BRD-K89930444 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41240 BRD-K89930444 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41580 BRD-K89930444 SKB 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.53
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).