CMap Candidate Details

Structure:
CMap ID: C31054
Pert ID: BRD-K90195324
Compound Name: bazedoxifene
Targets: ESR1
MoA: Selective estrogen receptor modulator
SMILES: Cc1c(-c2ccc(O)cc2)n(Cc2ccc(OCCN3CCCCCC3)cc2)c2ccc(O)cc12
InchiKey: UCJGJABZCDBEDK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90603 BRD-K90195324 HCT116 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90693 BRD-K90195324 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96513 BRD-K90195324 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127737 BRD-K90195324 A375 10 uM 24 h 0.2 0.81 0.0 0.0 0.0 0.0
127780 BRD-K90195324 A549 3.33 uM 24 h -0.27 -1.12 0.39 0.0 0.0 0.0
127860 BRD-K90195324 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127934 BRD-K90195324 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128026 BRD-K90195324 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128074 BRD-K90195324 YAPC 10 uM 24 h 0.0 0.0 0.0 0.38 1.34 1.72
135524 BRD-K90195324 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135561 BRD-K90195324 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135608 BRD-K90195324 HT29 0.01 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
135652 BRD-K90195324 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).