CMap Candidate Details

Structure:
CMap ID: C03112
Pert ID: BRD-K02227374
Compound Name: milnacipran
Targets: SLC6A2; SLC6A4
MoA: Serotonin reuptake inhibitor
SMILES: CCN(CC)C(=O)[C@@]1(C[C@@H]1CN)c1ccccc1
InchiKey: GJJFMKBJSRMPLA-HIFRSBDPSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24404 BRD-K02227374 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24548 BRD-K02227374 A549 10 uM 24 h -0.16 -0.66 0.0 0.28 0.99 0.39
24744 BRD-K02227374 HA1E 10 uM 6 h 0.27 1.11 0.25 0.29 1.04 0.55
24865 BRD-K02227374 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25001 BRD-K02227374 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25142 BRD-K02227374 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25486 BRD-K02227374 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).