CMap Candidate Details

Structure:
CMap ID: C31136
Pert ID: BRD-K90543092
Compound Name: levonorgestrel
Targets: PGR
MoA: Estrogen receptor agonist; Progesterone receptor agonist; Progesterone receptor antagonist; Glucocorticoid receptor antagonist
SMILES: CC[C@@]12CC[C@@H]3[C@H](CCC4=CC(=O)CC[C@@H]34)[C@H]1CC[C@@]2(O)C#C
InchiKey: WWYNJERNGUHSAO-ZWMUSQMVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49909 BRD-K90543092 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50076 BRD-K90543092 A549 10 uM 6 h -0.23 -0.96 0.09 0.0 0.0 0.0
50259 BRD-K90543092 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50608 BRD-K90543092 HT29 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.88 0.25
50696 BRD-K90543092 MCF??7.00 10 uM 24 h 0.22 0.91 0.04 0.25 0.89 0.2
50873 BRD-K90543092 PC3 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.34
51190 BRD-K90543092 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.99 0.5
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).