CMap Candidate Details

Structure:
CMap ID: C31147
Pert ID: BRD-K90574421
Compound Name: ipsapirone
Targets: HTR1A
MoA: Serotonin receptor agonist
SMILES: O=C1N(CCCCN2CCN(CC2)c2ncccn2)S(=O)(=O)c2ccccc12
InchiKey: TZJUVVIWVWFLCD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6909 BRD-K90574421 A375 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.89 0.26
7037 BRD-K90574421 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7362 BRD-K90574421 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7728 BRD-K90574421 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8031 BRD-K90574421 HT29 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.6
8118 BRD-K90574421 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
8733 BRD-K90574421 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51978 BRD-K90574421 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).