CMap Candidate Details

Structure:
CMap ID: C31224
Pert ID: BRD-K90825648
Compound Name: RS-127445
Targets: HTR2B
MoA: Serotonin receptor antagonist
SMILES: CC(C)c1cc(nc(N)n1)-c1ccc(F)c2ccccc12
InchiKey: ZZZQXCUPAJFVBN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
128150 BRD-K90825648 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128240 BRD-K90825648 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128319 BRD-K90825648 MDAMB231 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128340 BRD-K90825648 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128362 BRD-K90825648 THP1 3.33 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
135762 BRD-K90825648 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135824 BRD-K90825648 HA1E 0.01 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.04
135863 BRD-K90825648 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135914 BRD-K90825648 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.29 1.01 0.44
135954 BRD-K90825648 HT29 0.03 uM 24 h 0.27 1.14 0.32 -0.26 -0.89 0.26
136004 BRD-K90825648 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.27
136035 BRD-K90825648 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136150 BRD-K90825648 YAPC 0.03 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).