CMap Candidate Details

Structure:
CMap ID: C03137
Pert ID: BRD-K02283807
Compound Name: GR-32191
Targets: TBXA2R
MoA: Thromboxane receptor antagonist
SMILES: O[C@H]1C[C@H](OCc2ccc(cc2)c3ccccc3)[C@H](CC/C=CCCC(=O)O)[C@H]1N4CCCCC4
InchiKey: GQGRDYWMOPRROR-XUSMOFMBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1530 BRD-K02283807 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1865 BRD-K02283807 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2362 BRD-K02283807 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2727 BRD-K02283807 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41701 BRD-K02283807 A375 10 uM 6 h 0.25 1.04 0.15 0.24 0.86 0.16
41897 BRD-K02283807 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42260 BRD-K02283807 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42596 BRD-K02283807 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42901 BRD-K02283807 HT29 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.32
43145 BRD-K02283807 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43456 BRD-K02283807 NPC 10 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.37
99967 BRD-K02283807 U2OS 10 uM 6 h 0.23 0.94 0.06 0.22 0.79 0.07
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).