CMap Candidate Details

Structure:
CMap ID: C03140
Pert ID: BRD-K02292852
Compound Name: cefoperazone
Targets: --
MoA: --
SMILES: CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(CSc4nnnn4C)=C(N3C2=O)C(O)=O)c2ccc(O)cc2)C(=O)C1=O
InchiKey: GCFBRXLSHGKWDP-XCGNWRKASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91429 BRD-K02292852 HUH7 4 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
117781 BRD-K02292852 HA1E 3.33 uM 24 h 0.2 0.84 0.0 0.0 0.0 0.0
117832 BRD-K02292852 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117882 BRD-K02292852 HEPG2 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122900 BRD-K02292852 HEK293 0.37 uM 24 h -0.24 -0.98 0.13 0.22 0.79 0.07
122976 BRD-K02292852 HT29 0.04 uM 24 h 0.27 1.11 0.26 -0.31 -1.04 0.66
123025 BRD-K02292852 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123115 BRD-K02292852 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123148 BRD-K02292852 PC3 0.37 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.55
123186 BRD-K02292852 THP1 0.125 uM 24 h 0.17 0.69 0.0 0.0 0.0 0.0
131212 BRD-K02292852 A375 0.25 uM 24 h -0.26 -1.08 0.3 0.0 0.0 0.0
131248 BRD-K02292852 A549 0.01 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
131308 BRD-K02292852 HELA 2.22 uM 24 h -0.3 -1.24 0.67 0.21 0.76 0.05
131362 BRD-K02292852 HUVEC 0.03 uM 24 h 0.26 1.09 0.23 0.0 0.0 0.0
131402 BRD-K02292852 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131440 BRD-K02292852 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 -0.36 -1.23 1.25
131499 BRD-K02292852 YAPC 0.01 uM 24 h 0.18 0.74 0.0 -0.22 -0.73 0.05
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).