CMap Candidate Details

Structure:
CMap ID: C31480
Pert ID: BRD-K91691979
Compound Name: BRD-K91691979
Targets: GBA
MoA: Glucosylceramidase inhibitor
SMILES: CC(C)(C)Oc1ccccc1Nc2nc(NCCO)nc(n2)N3CCCC3
InchiKey: YLYZGVPSUIZOCY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
14011 BRD-K91691979 A375 10 uM 6 h -0.2 -0.83 0.0 -0.25 -0.85 0.2
14179 BRD-K91691979 A549 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.68 0.02
14682 BRD-K91691979 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
14912 BRD-K91691979 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
15158 BRD-K91691979 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
15549 BRD-K91691979 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.3 1.58
15845 BRD-K91691979 PC3 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.99 0.5
15971 BRD-K91691979 VCAP 10 uM 24 h 0.2 0.82 0.0 0.0 0.0 0.0
115211 BRD-K91691979 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).