CMap Candidate Details

Structure:
CMap ID: C31485
Pert ID: BRD-K91699951
Compound Name: benzonatate
Targets: SCN5A
MoA: Local anesthetic
SMILES: CCCCNc1ccc(cc1)C(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOC
InchiKey: MAFMQEKGGFWBAB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5237 BRD-K91699951 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5373 BRD-K91699951 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5696 BRD-K91699951 HCC515 10 uM 24 h 0.0 0.0 0.0 0.3 1.08 0.65
6301 BRD-K91699951 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6601 BRD-K91699951 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39369 BRD-K91699951 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39824 BRD-K91699951 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40114 BRD-K91699951 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40375 BRD-K91699951 HT29 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.94 0.38
40533 BRD-K91699951 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40922 BRD-K91699951 NEU 10 uM 24 h -0.23 -0.97 0.11 -0.3 -1.01 0.56
41246 BRD-K91699951 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).