CMap Candidate Details

Structure:
CMap ID: C31512
Pert ID: BRD-K91781484
Compound Name: BRD-K91781484
Targets: NFE2L2
MoA: NRF2 activator
SMILES: S=c1ccss1
InchiKey: LZENMJMJWQSSNJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
44460 BRD-K91781484 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44734 BRD-K91781484 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45051 BRD-K91781484 ASC 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
45337 BRD-K91781484 HEPG2 10 uM 6 h 0.34 1.41 1.03 0.0 0.0 0.0
45596 BRD-K91781484 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45858 BRD-K91781484 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.42 -1.4 2.02
46804 BRD-K91781484 SKB 10 uM 24 h 0.0 0.0 0.0 0.36 1.26 1.29
96025 BRD-K91781484 PHH 10 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
98251 BRD-K91781484 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
98500 BRD-K91781484 NEU 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.2 1.21
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).