CMap Candidate Details

Structure:
CMap ID: C31564
Pert ID: BRD-K91938660
Compound Name: memantine
Targets: GRIN1
MoA: Glutamate receptor antagonist
SMILES: C[C@@]1(C[C@@H]2C[C@]3(C)C1)C[C@](N)(C2)C3
InchiKey: BUGYDGFZZOZRHP-CDECOKDKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24503 BRD-K91938660 A375 10 uM 6 h -0.2 -0.81 0.0 -0.25 -0.85 0.19
24701 BRD-K91938660 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24966 BRD-K91938660 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25054 BRD-K91938660 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25270 BRD-K91938660 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25444 BRD-K91938660 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.19 -0.66 0.01
91171 BRD-K91938660 HUH7 20 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).