CMap Candidate Details

Structure:
CMap ID: C31571
Pert ID: BRD-K91966436
Compound Name: daunorubicin
Targets: TOP2A
MoA: RNA synthesis inhibitor; Topoisomerase inhibitor
SMILES: COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=O
InchiKey: STQGQHZAVUOBTE-INJOJONLSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
51862 BRD-K91966436 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95552 BRD-K91966436 A549 10 uM 6 h -0.26 -1.08 0.3 0.36 1.27 1.34
95563 BRD-K91966436 MCF??7.00 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95650 BRD-K91966436 U2OS 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).