CMap Candidate Details

Structure:
CMap ID: C31596
Pert ID: BRD-K92041145
Compound Name: O6-benzylguanine
Targets: --
MoA: --
SMILES: Nc1nc(OCc2ccccc2)c2[nH]cnc2n1
InchiKey: KRWMERLEINMZFT-UHFFFAOYSA-N
Compound Aliases: O-6-BENZYLGUANINE

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
115952 BRD-K92041145 A375 0.04 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.76
115988 BRD-K92041145 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116070 BRD-K92041145 HCC515 0.125 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.12
116113 BRD-K92041145 HEPG2 10 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
116239 BRD-K92041145 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127828 BRD-K92041145 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127875 BRD-K92041145 HEK293 3.33 uM 24 h 0.29 1.19 0.42 0.0 0.0 0.0
127949 BRD-K92041145 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128002 BRD-K92041145 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.34
128083 BRD-K92041145 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135576 BRD-K92041145 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.24
135618 BRD-K92041145 HT29 0.08 uM 24 h -0.26 -1.08 0.29 -0.34 -1.14 1.03
135667 BRD-K92041145 JURKAT 0.08 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.13
135700 BRD-K92041145 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.22
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).