CMap Candidate Details

Structure:
CMap ID: C03179
Pert ID: BRD-K02407574
Compound Name: parbendazole
Targets: TUBB
MoA: Tubulin inhibitor
SMILES: CCCCc1ccc2[nH]c(NC(=O)OC)nc2c1
InchiKey: YRWLZFXJFBZBEY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1216 BRD-K02407574 PC3 10 uM 24 h -0.27 -1.13 0.4 0.0 0.0 0.0
9334 BRD-K02407574 AGS 0.3 uM 6 h 0.0 0.0 0.0 0.21 0.76 0.05
9640 BRD-K02407574 H1299 0.3 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10438 BRD-K02407574 HCT116 0.3 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11390 BRD-K02407574 NCIH2073 0.3 uM 6 h -0.2 -0.82 0.0 0.0 0.0 0.0
11962 BRD-K02407574 NCIH596 0.3 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
12245 BRD-K02407574 NOMO1 0.3 uM 6 h -0.21 -0.86 0.02 0.0 0.0 0.0
12993 BRD-K02407574 THP1 0.3 uM 6 h 0.29 1.22 0.47 0.0 0.0 0.0
13187 BRD-K02407574 U937 0.3 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.65
13439 BRD-K02407574 VCAP 0.3 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.26
52061 BRD-K02407574 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96290 BRD-K02407574 U2OS 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.16 1.11
97689 BRD-K02407574 NKDBA 10 uM 24 h 0.27 1.13 0.3 0.41 1.47 2.24
117348 BRD-K02407574 A375 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117386 BRD-K02407574 A549 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117426 BRD-K02407574 HA1E 10 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.58
117471 BRD-K02407574 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117519 BRD-K02407574 HEPG2 10 uM 24 h -0.21 -0.89 0.04 -0.29 -0.97 0.45
117562 BRD-K02407574 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).