CMap Candidate Details

Structure:
CMap ID: C31791
Pert ID: BRD-K92731339
Compound Name: perindopril
Targets: ACE
MoA: Angiotensin converting enzyme inhibitor
SMILES: CCC[C@H](N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O)C(=O)OCC
InchiKey: IPVQLZZIHOAWMC-QXKUPLGCSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5697 BRD-K92731339 HCC515 10 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.19
6602 BRD-K92731339 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37418 BRD-K92731339 A549 10 uM 6 h 0.2 0.83 0.0 0.0 0.0 0.0
37762 BRD-K92731339 ASC 10 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
37959 BRD-K92731339 HEPG2 10 uM 6 h -0.22 -0.92 0.06 0.0 0.0 0.0
38576 BRD-K92731339 NPC 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.49
38796 BRD-K92731339 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96548 BRD-K92731339 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121800 BRD-K92731339 HT29 0.37 uM 24 h 0.27 1.11 0.25 0.0 0.0 0.0
121821 BRD-K92731339 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.43
129762 BRD-K92731339 A375 0.01 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
129798 BRD-K92731339 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129839 BRD-K92731339 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129877 BRD-K92731339 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129965 BRD-K92731339 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.55
130050 BRD-K92731339 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130121 BRD-K92731339 THP1 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130167 BRD-K92731339 YAPC 2.22 uM 24 h -0.31 -1.28 0.77 0.29 1.02 0.48
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).