CMap Candidate Details

Structure:
CMap ID: C31836
Pert ID: BRD-K92848252
Compound Name: diminazene-aceturate
Targets: AOC1
MoA: DNA intercalator; Topoisomerase inhibitor; Angiotensin converting enzyme activator
SMILES: NC(=N)c1ccc(NN=Nc2ccc(cc2)C(N)=N)cc1
InchiKey: XNYZHCFCZNMTFY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
128370 BRD-K92848252 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128419 BRD-K92848252 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128529 BRD-K92848252 JURKAT 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128622 BRD-K92848252 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128672 BRD-K92848252 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128702 BRD-K92848252 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.38
128753 BRD-K92848252 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136163 BRD-K92848252 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136209 BRD-K92848252 HA1E 0.03 uM 24 h 0.26 1.07 0.2 0.0 0.0 0.0
136251 BRD-K92848252 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136284 BRD-K92848252 HT29 0.03 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.11
136302 BRD-K92848252 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.3
136330 BRD-K92848252 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).