CMap Candidate Details

Structure:
CMap ID: C31909
Pert ID: BRD-K93034159
Compound Name: cladribine
Targets: ADA
MoA: Adenosine deaminase inhibitor; Ribonucleoside reductase inhibitor
SMILES: Nc1nc(Cl)nc2n(cnc12)[C@H]1C[C@H](O)[C@@H](CO)O1
InchiKey: PTOAARAWEBMLNO-KVQBGUIXSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
22888 BRD-K93034159 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23193 BRD-K93034159 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24242 BRD-K93034159 VCAP 10 uM 24 h -0.24 -1.01 0.15 0.0 0.0 0.0
49913 BRD-K93034159 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50612 BRD-K93034159 HT29 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.86 0.22
50701 BRD-K93034159 MCF??7.00 10 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
52349 BRD-K93034159 PC3 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.46 15.35
95385 BRD-K93034159 U2OS 10 uM 24 h -0.26 -1.07 0.27 0.0 0.0 0.0
128230 BRD-K93034159 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128309 BRD-K93034159 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.55
128356 BRD-K93034159 THP1 1.11 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
135780 BRD-K93034159 A549 2.22 uM 24 h -0.22 -0.91 0.05 0.2 0.71 0.02
135816 BRD-K93034159 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135855 BRD-K93034159 HEK293 0.25 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
135904 BRD-K93034159 HELA 2.22 uM 24 h 0.26 1.08 0.21 0.25 0.9 0.21
135993 BRD-K93034159 JURKAT 0.74 uM 24 h -0.23 -0.95 0.09 -0.21 -0.71 0.03
136139 BRD-K93034159 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).