CMap Candidate Details

Structure:
CMap ID: C31924
Pert ID: BRD-K93095519
Compound Name: SJ-172550
Targets: MDM4
MoA: MDM inhibitor
SMILES: CCOc1cc(cc(Cl)c1OCC(=O)OC)C=C1C(=O)N(N=C/1C)c1ccccc1
InchiKey: RKKFQJXGAQWHBZ-YVLHZVERSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9254 BRD-K93095519 A549 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9856 BRD-K93095519 H1299 12 uM 6 h 0.28 1.15 0.34 0.31 1.09 0.67
10096 BRD-K93095519 HA1E 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10228 BRD-K93095519 HCC515 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10630 BRD-K93095519 HCT116 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10882 BRD-K93095519 HEPG2 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11110 BRD-K93095519 HT29 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11226 BRD-K93095519 MCF??7.00 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11616 BRD-K93095519 NCIH2073 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11873 BRD-K93095519 NCIH508 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12173 BRD-K93095519 NCIH596 12 uM 6 h 0.0 0.0 0.0 -0.46 -1.56 15.65
12411 BRD-K93095519 NOMO1 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12552 BRD-K93095519 PC3 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12905 BRD-K93095519 SW480 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13078 BRD-K93095519 THP1 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13517 BRD-K93095519 VCAP 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96034 BRD-K93095519 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97293 BRD-K93095519 HAP1 0.66 uM 24 h 0.23 0.97 0.08 -0.27 -0.91 0.31
97359 BRD-K93095519 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).