CMap Candidate Details

Structure:
CMap ID: C31956
Pert ID: BRD-K93188295
Compound Name: ARC-239
Targets: ADRA2B
MoA: Adrenergic receptor antagonist
SMILES: COc1ccccc1N1CCN(CCN2C(=O)c3ccccc3C(C)(C)C2=O)CC1
InchiKey: JFNKXGOEOQCXDM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6815 BRD-K93188295 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7040 BRD-K93188295 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7496 BRD-K93188295 HA1E 10 uM 6 h 0.24 1.0 0.11 0.0 0.0 0.0
7730 BRD-K93188295 HCC515 10 uM 6 h 0.28 1.15 0.32 -0.25 -0.84 0.18
7926 BRD-K93188295 HT29 10 uM 24 h -0.23 -0.96 0.09 -0.3 -1.0 0.55
8119 BRD-K93188295 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8415 BRD-K93188295 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8736 BRD-K93188295 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).