CMap Candidate Details

Structure:
CMap ID: C31963
Pert ID: BRD-K93201660
Compound Name: ML-7
Targets: MYLK
MoA: Myosin light chain kinase inhibitor
SMILES: Ic1cccc2c(cccc12)S(=O)(=O)N3CCCNCC3
InchiKey: GEHJIACZUFWBTK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2944 BRD-K93201660 HA1E 10 uM 24 h 0.26 1.09 0.22 0.3 1.07 0.62
3410 BRD-K93201660 HCC515 10 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.63
3565 BRD-K93201660 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3896 BRD-K93201660 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41987 BRD-K93201660 A549 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
42497 BRD-K93201660 ASC 10 uM 24 h -0.24 -0.99 0.14 0.0 0.0 0.0
42807 BRD-K93201660 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43094 BRD-K93201660 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43364 BRD-K93201660 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43672 BRD-K93201660 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43973 BRD-K93201660 PHH 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
99509 BRD-K93201660 U2OS 25 uM 6 h 0.0 0.0 0.0 0.33 1.18 0.97
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).