CMap Candidate Details

Structure:
CMap ID: C31980
Pert ID: BRD-K93255255
Compound Name: indoximod
Targets: IDO1
MoA: Indoleamine 2,3-dioxygenase inhibitor
SMILES: Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12
InchiKey: ZADWXFSZEAPBJS-SNVBAGLBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
128129 BRD-K93255255 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128181 BRD-K93255255 HT29 1.11 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
128206 BRD-K93255255 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128285 BRD-K93255255 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.24
128345 BRD-K93255255 THP1 0.125 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.47
135753 BRD-K93255255 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135795 BRD-K93255255 HA1E 0.25 uM 24 h -0.29 -1.19 0.53 0.0 0.0 0.0
135840 BRD-K93255255 HEK293 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135880 BRD-K93255255 HELA 0.08 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.47
135969 BRD-K93255255 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136020 BRD-K93255255 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 -0.3 -0.99 0.51
136048 BRD-K93255255 PC3 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136115 BRD-K93255255 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).