CMap Candidate Details

Structure:
CMap ID: C00032
Pert ID: BRD-A01346607
Compound Name: flumetasone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: C[C@@H]1CC2C3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
InchiKey: WXURHACBFYSXBI-DRBBXQFKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3999 BRD-A01346607 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.01
4510 BRD-A01346607 HCC515 10 uM 6 h 0.25 1.05 0.17 0.0 0.0 0.0
4602 BRD-A01346607 PC3 10 uM 24 h -0.23 -0.97 0.11 0.0 0.0 0.0
37032 BRD-A01346607 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37319 BRD-A01346607 A549 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.37
37423 BRD-A01346607 ASC 10 uM 24 h -0.24 -0.98 0.13 0.0 0.0 0.0
37776 BRD-A01346607 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37970 BRD-A01346607 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38120 BRD-A01346607 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38277 BRD-A01346607 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38589 BRD-A01346607 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).