CMap Candidate Details

Structure:
CMap ID: C32000
Pert ID: BRD-K93331255
Compound Name: lypressin
Targets: AVPR1A; AVPR1B; AVPR2
MoA: Vasopressin receptor agonist
SMILES: NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O
InchiKey: BJFIDCADFRDPIO-DZCXQCEKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33703 BRD-K93331255 A375 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.93 0.34
33858 BRD-K93331255 A549 10 uM 24 h 0.26 1.08 0.22 -0.31 -1.06 0.73
34212 BRD-K93331255 ASC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.73
34447 BRD-K93331255 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34993 BRD-K93331255 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35229 BRD-K93331255 HT29 10 uM 6 h 0.0 0.0 0.0 0.24 0.85 0.14
35476 BRD-K93331255 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.99 0.51
35639 BRD-K93331255 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35867 BRD-K93331255 NPC 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.22
36013 BRD-K93331255 PC3 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.37
36384 BRD-K93331255 PHH 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.67 0.01
36685 BRD-K93331255 SKB 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
36896 BRD-K93331255 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.79 0.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).