CMap Candidate Details

Structure:
CMap ID: C32010
Pert ID: BRD-K93367411
Compound Name: BRD-K93367411
Targets: KEAP1
MoA: Kelch-like ECH-associated protein ligand
SMILES: OC(=O)[C@@H]1CCCC[C@@H]1C(=O)N1CCc2ccccc2[C@H]1CN1C(=O)c2ccccc2C1=O
InchiKey: LNENLABLFGGAFF-BHDDXSALSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
117051 BRD-K93367411 A549 0.37 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.71
117132 BRD-K93367411 HCC515 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117226 BRD-K93367411 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.21
119113 BRD-K93367411 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.42
119193 BRD-K93367411 A375 0.37 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.74
119249 BRD-K93367411 HA1E 100 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119308 BRD-K93367411 HEPG2 1.25 uM 24 h -0.28 -1.16 0.47 0.0 0.0 0.0
119358 BRD-K93367411 MCF??7.00 4 uM 24 h -0.18 -0.76 0.0 -0.36 -1.2 1.21
119381 BRD-K93367411 PC3 0.37 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.27
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).