CMap Candidate Details

Structure:
CMap ID: C32076
Pert ID: BRD-K93568044
Compound Name: hydrocortisone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: C[C@@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@]1(O)C(=O)CO
InchiKey: JYGXADMDTFJGBT-JEFZWPMTSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49915 BRD-K93568044 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50079 BRD-K93568044 A549 10 uM 6 h 0.23 0.98 0.09 -0.33 -1.12 0.94
50264 BRD-K93568044 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50433 BRD-K93568044 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.42 -1.42 2.02
50614 BRD-K93568044 HT29 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.61
50791 BRD-K93568044 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.21 1.24
50876 BRD-K93568044 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51196 BRD-K93568044 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91424 BRD-K93568044 HUH7 10 uM 72 h 0.29 1.2 0.42 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).