CMap Candidate Details

Structure:
CMap ID: C03214
Pert ID: BRD-K02526760
Compound Name: QS-11
Targets: ARFGAP1
MoA: ARFGAP inhibitor
SMILES: OC[C@H](Cc1ccccc1)Nc1nc(Oc2ccc3CCCc3c2)nc2n(Cc3ccc(cc3)-c3ccccc3)cnc12
InchiKey: DOKZLKDGUQWMSX-HKBQPEDESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8897 BRD-K02526760 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9082 BRD-K02526760 A549 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.44 15.35
9335 BRD-K02526760 AGS 10 uM 6 h 0.0 0.0 0.0 -0.46 -1.56 15.65
9641 BRD-K02526760 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9941 BRD-K02526760 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.13
10192 BRD-K02526760 HCC515 10 uM 24 h 0.22 0.9 0.03 -0.33 -1.12 0.95
10439 BRD-K02526760 HCT116 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.58
10710 BRD-K02526760 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.4 -1.36 2.02
10928 BRD-K02526760 HT29 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
11198 BRD-K02526760 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.42 3.29
11391 BRD-K02526760 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11693 BRD-K02526760 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11963 BRD-K02526760 NCIH596 10 uM 6 h -0.25 -1.06 0.24 -0.42 -1.4 2.02
12246 BRD-K02526760 NOMO1 10 uM 6 h -0.24 -1.01 0.17 -0.48 -1.6 15.65
12515 BRD-K02526760 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12707 BRD-K02526760 SW480 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.27 1.43
13037 BRD-K02526760 THP1 10 uM 6 h 0.0 0.0 0.0 -0.45 -1.53 15.35
13188 BRD-K02526760 U937 10 uM 6 h -0.23 -0.94 0.08 0.0 0.0 0.0
13566 BRD-K02526760 VCAP 10 uM 6 h -0.29 -1.2 0.56 -0.33 -1.11 0.92
98860 BRD-K02526760 NEU 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.22
99125 BRD-K02526760 NPC 10 uM 24 h -0.18 -0.76 0.0 -0.35 -1.19 1.15
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).