CMap Candidate Details

Structure:
CMap ID: C32213
Pert ID: BRD-K94012289
Compound Name: OSI-027
Targets: MTOR
MoA: MTOR inhibitor
SMILES: COC1=CC=CC2=CC(=C3C4=C(N=CNN4C(=N3)C5CCC(CC5)C(=O)O)N)N=C21
InchiKey: CDNMDRUIGNHEMR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
92404 BRD-K94012289 A375 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92429 BRD-K94012289 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92459 BRD-K94012289 BT20 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92493 BRD-K94012289 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92526 BRD-K94012289 HME1 0.04 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.15
92576 BRD-K94012289 HS578T 10 uM 24 h 0.27 1.13 0.29 0.0 0.0 0.0
92624 BRD-K94012289 HT29 10 uM 24 h 0.17 0.7 0.0 0.0 0.0 0.0
92660 BRD-K94012289 LNCAP 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92727 BRD-K94012289 MCF10A 0.04 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92758 BRD-K94012289 MCF??7.00 10 uM 3 h 0.0 0.0 0.0 -0.31 -1.05 0.71
92769 BRD-K94012289 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92801 BRD-K94012289 PC3 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.74
92847 BRD-K94012289 SKBR3 10 uM 3 h 0.0 0.0 0.0 -0.38 -1.26 1.38
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).