CMap Candidate Details

Structure:
CMap ID: C32290
Pert ID: BRD-K94270326
Compound Name: ecopipam
Targets: DRD1; DRD5
MoA: Dopamine receptor antagonist
SMILES: CN1CCc2cc(Cl)c(O)cc2[C@@H]3[C@@H]1CCc4ccccc34
InchiKey: DMJWENQHWZZWDF-PKOBYXMFSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1665 BRD-K94270326 HA1E 10 uM 24 h -0.3 -1.26 0.71 -0.28 -0.95 0.41
2012 BRD-K94270326 HCC515 10 uM 24 h 0.0 0.0 0.0 0.42 1.48 2.24
2448 BRD-K94270326 PC3 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.3
2664 BRD-K94270326 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39236 BRD-K94270326 A375 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
39528 BRD-K94270326 A549 10 uM 6 h -0.28 -1.17 0.48 0.0 0.0 0.0
40132 BRD-K94270326 HEPG2 10 uM 6 h -0.31 -1.29 0.77 0.0 0.0 0.0
40390 BRD-K94270326 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40541 BRD-K94270326 MCF??7.00 10 uM 24 h 0.24 1.0 0.11 0.0 0.0 0.0
40938 BRD-K94270326 NEU 10 uM 24 h 0.23 0.95 0.07 0.0 0.0 0.0
41263 BRD-K94270326 NPC 10 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.33
41604 BRD-K94270326 SKB 10 uM 24 h 0.22 0.94 0.05 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).