CMap Candidate Details

Structure:
CMap ID: C32302
Pert ID: BRD-K94294671
Compound Name: OSI-027
Targets: MTOR
MoA: MTOR inhibitor
SMILES: COc1cccc2cc([nH]c12)-c1nc([C@@H]2CC[C@@H](CC2)C(O)=O)n2ncnc(N)c12
InchiKey: JROFGZPOBKIAEW-TXEJJXNPSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33571 BRD-K94294671 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33946 BRD-K94294671 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34214 BRD-K94294671 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34449 BRD-K94294671 HA1E 10 uM 6 h -0.2 -0.83 0.0 0.0 0.0 0.0
34717 BRD-K94294671 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34995 BRD-K94294671 HEPG2 10 uM 6 h -0.21 -0.85 0.01 0.0 0.0 0.0
35230 BRD-K94294671 HT29 10 uM 6 h 0.0 0.0 0.0 0.16 0.56 0.0
35869 BRD-K94294671 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36116 BRD-K94294671 PC3 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.31
36385 BRD-K94294671 PHH 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
36687 BRD-K94294671 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37018 BRD-K94294671 VCAP 10 uM 6 h -0.23 -0.94 0.08 0.0 0.0 0.0
91562 BRD-K94294671 BT20 10 uM 6 h -0.17 -0.71 0.0 -0.39 -1.3 1.67
91613 BRD-K94294671 HS578T 2.22 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91629 BRD-K94294671 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.36
91670 BRD-K94294671 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
91721 BRD-K94294671 MDAMB231 10 uM 6 h -0.25 -1.05 0.24 0.0 0.0 0.0
91783 BRD-K94294671 SKBR3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).