CMap Candidate Details

Structure:
CMap ID: C32338
Pert ID: BRD-K94397152
Compound Name: ribavirin
Targets: IMPDH1
MoA: Antiviral
SMILES: NC(=O)c1ncn(n1)[C@H]1O[C@H](CO)[C@@H](O)[C@H]1O
InchiKey: IWUCXVSUMQZMFG-DJSMDIAISA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
128379 BRD-K94397152 A549 3.33 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.27
128434 BRD-K94397152 HEK293 10 uM 24 h 0.24 1.02 0.12 0.0 0.0 0.0
128476 BRD-K94397152 HELA 3.33 uM 24 h 0.18 0.73 0.0 0.0 0.0 0.0
128544 BRD-K94397152 JURKAT 0.04 uM 24 h -0.25 -1.02 0.18 0.0 0.0 0.0
128592 BRD-K94397152 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128636 BRD-K94397152 MDAMB231 3.33 uM 24 h 0.23 0.96 0.08 0.3 1.06 0.61
128678 BRD-K94397152 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128716 BRD-K94397152 THP1 10 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.57
128764 BRD-K94397152 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136176 BRD-K94397152 A375 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136221 BRD-K94397152 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136287 BRD-K94397152 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136341 BRD-K94397152 MCF??7.00 0.74 uM 24 h 0.28 1.18 0.39 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).