CMap Candidate Details

Structure:
CMap ID: C00324
Pert ID: BRD-A12896037
Compound Name: cisapride
Targets: HTR4; KCNH2
MoA: Serotonin receptor agonist
SMILES: COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC
InchiKey: DCSUBABJRXZOMT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122246 BRD-A12896037 A375 3.33 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.68
122283 BRD-A12896037 A549 1.11 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.39
122386 BRD-A12896037 MCF??7.00 10 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
122412 BRD-A12896037 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122436 BRD-A12896037 PC3 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.06
122468 BRD-A12896037 THP1 10 uM 24 h 0.24 1.0 0.11 0.0 0.0 0.0
122513 BRD-A12896037 YAPC 1.11 uM 24 h -0.31 -1.3 0.81 -0.35 -1.18 1.14
130586 BRD-A12896037 HA1E 2.22 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
130619 BRD-A12896037 HEK293 0.08 uM 24 h -0.29 -1.22 0.61 0.24 0.86 0.16
130660 BRD-A12896037 HELA 0.74 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.22
130702 BRD-A12896037 HT29 2.22 uM 24 h 0.17 0.72 0.0 0.3 1.05 0.57
130737 BRD-A12896037 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).