CMap Candidate Details

Structure:
CMap ID: C32407
Pert ID: BRD-K94649603
Compound Name: taxifolin
Targets: ADIPOR2
MoA: Opioid receptor antagonist
SMILES: O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c1ccc(O)c(O)c1
InchiKey: CXQWRCVTCMQVQX-LSDHHAIUSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24508 BRD-K94649603 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24630 BRD-K94649603 A549 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.95
24823 BRD-K94649603 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25204 BRD-K94649603 PC3 10 uM 24 h -0.28 -1.15 0.43 0.0 0.0 0.0
25452 BRD-K94649603 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119670 BRD-K94649603 HEPG2 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119708 BRD-K94649603 HT29 10 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.12
119756 BRD-K94649603 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.7
119796 BRD-K94649603 MCF??7.00 0.125 uM 24 h 0.19 0.77 0.0 -0.23 -0.79 0.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).