CMap Candidate Details

Structure:
CMap ID: C03246
Pert ID: BRD-K02607075
Compound Name: tubocurarine
Targets: CHRNA2; HTR3A
MoA: Acetylcholine receptor antagonist
SMILES: COc1cc2CC[N+](C)(C)[C@@H]3Cc4ccc(O)c(Oc5cc6[C@H](Cc7cccc(Oc(c1O)c32)c7)N(C)CCc6cc5OC)c4
InchiKey: MZTXBESCVZFFQE-XLTVJXRZSA-O
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1723 BRD-K02607075 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.81 0.13
1867 BRD-K02607075 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2206 BRD-K02607075 PC3 10 uM 24 h 0.23 0.95 0.06 0.0 0.0 0.0
2694 BRD-K02607075 VCAP 10 uM 6 h 0.0 0.0 0.0 0.24 0.86 0.16
41703 BRD-K02607075 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41898 BRD-K02607075 A549 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.57
42262 BRD-K02607075 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42598 BRD-K02607075 HEPG2 10 uM 6 h 0.19 0.81 0.0 0.0 0.0 0.0
42903 BRD-K02607075 HT29 10 uM 6 h -0.24 -1.01 0.16 0.0 0.0 0.0
43147 BRD-K02607075 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.02
43764 BRD-K02607075 PHH 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.71 0.03
44045 BRD-K02607075 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).