CMap Candidate Details

Structure:
CMap ID: C32465
Pert ID: BRD-K94853001
Compound Name: Mps1-IN-1
Targets: --
MoA: --
SMILES: COc1cc(ccc1Nc1cc(Nc2ccccc2S(=O)(=O)C(C)C)c2cc[nH]c2n1)N1CCC(O)CC1
InchiKey: NMJMRSQTDLRCRQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
50 BRD-K94853001 BJAB 10 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
84 BRD-K94853001 HBL1 0.66 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.57
120 BRD-K94853001 K562 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
172 BRD-K94853001 KMS34 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.21
214 BRD-K94853001 NALM6 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
253 BRD-K94853001 OCILY10 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
284 BRD-K94853001 OCILY19 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
349 BRD-K94853001 OCILY3 10 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
370 BRD-K94853001 SKMEL5 10 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.21
419 BRD-K94853001 THP1 10 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
440 BRD-K94853001 TMD8 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.34
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).